PTAC (Packaged Terminal Air Conditioner) units are installed through a wall and serve individual rooms, while VTAC (Vertical Terminal Air Conditioner) units are installed vertically in a closet and can serve multiple spaces. VTACs are often chosen for suites or multi-room layouts where a single unit can manage a larger area. PTACs are more common in standard guest rooms because they are easier to replace and maintain individually. Choosing the right system depends on your property layout and operational needs.